GLP-1 & GLP-1 + GIP · Weekly injection
Weight Loss Support
- ·Starting price applies to 3-month plans
- ·Semaglutide Microdose
- ·Monthly plans available
- ·Cancel anytime
Starting at
$79 /mo
Dieting harder doesn't quiet hunger. GLP-1 medications do. Compounded semaglutide or tirzepatide, prescribed online and shipped to your door.
- Licensed physician sets your dose
- Free shipping, no insurance needed
- Not charged unless prescribed
GLP-1 is a hormone your gut releases after you eat. It tells your brain you're full, slows how quickly your stomach empties and helps regulate blood sugar. GLP-1 medications mimic it for longer, so hunger and cravings quiet down and smaller portions feel like enough. Semaglutide acts on GLP-1. Tirzepatide acts on GLP-1 and a second hormone, GIP.
Adults carrying extra weight who haven't been able to keep it off with diet and exercise alone. A licensed physician reviews your health history, height and weight to confirm treatment is safe and right for you.
Your compounded semaglutide or tirzepatide vial (with vitamin B6), sterile syringes, alcohol prep pads and step-by-step injection instructions. It ships free, with ongoing access to your care team. You inject once a week, a small subcutaneous shot that takes under a minute.
What's In Your Monthly Kit
- Custom-compounded injection vial
- Sterile syringes & needles
- Alcohol prep pads
- Step-by-step injection guide
- FREE physician consultation included
- Free priority shipping
Everything you need, delivered monthly to your door
TWO MEDICATIONS · ONE GOAL
GLP-1 or GLP-1 + GIP: choose your medication
Both are once-weekly injections that turn down hunger at the source. Each comes as Microdose, a low, steady dose, or Personalized Dose, which steps up as your physician directs. Your physician confirms the right fit, and you pick your plan at checkout after your assessment.
Semaglutide
GLP-1Compounded Semaglutide + B6
1 pathway
GLP-1, the gut's "I'm full" hormone
- The lowest-cost way to start
- Quiets cravings and helps you feel full sooner
- One small injection, once a week
$79 first month
Microdose, 3-month plan: then $99/mo, $319 every 3 months after
Monthly from $99 · Personalized Dose from $109
Start with Semaglutide
Tirzepatide
GLP-1 + GIPCompounded Tirzepatide + B6
2 pathways
GLP-1 plus GIP, a second appetite hormone
- Dual-action: two hormone pathways instead of one
- Quiets cravings and helps you feel full sooner
- One small injection, once a week
$133/mo to start
Microdose, 3-month plan: $397, then $447 every 3 months
Monthly from $149 · Personalized Dose from $179
Start with TirzepatideNot charged unless prescribed. Free shipping, cancel anytime. Compounded semaglutide and tirzepatide are not FDA-approved.
The science
Hunger isn't a willpower problem. It's hormones.
After you eat, your gut releases hormones that tell your body you've had enough. GLP-1 medications mimic those signals and keep them going for days instead of minutes.
In your brain
Turns down hunger signals and the constant "food noise", so cravings lose their grip.
In your stomach
Slows how quickly your stomach empties, so you feel full sooner and stay full longer.
In your pancreas
Helps release insulin when blood sugar rises, for steadier energy and fewer crashes.
GLP-1 vs. GLP-1 + GIP
Semaglutide: One pathway. Semaglutide mimics GLP-1, the gut's "I'm full" hormone, and keeps the signal going all week instead of fading within minutes.
Tirzepatide: Two pathways. Tirzepatide mimics GLP-1 and GIP, a second gut hormone involved in appetite and how your body handles sugar and fat, so it works on two pathways instead of one.
Your dose, your pace
Physician-guided from the first week
- 1
Start low. A small weekly dose so your body can adjust.
- 2
Check in. Your care team asks how you feel and how your appetite has changed.
- 3
Adjust. Your physician steps the dose up, holds it, or keeps you on Microdose.
- 4
Maintain. Stay on the dose that works for you, with support whenever you need it.
Real patients. Real results.
Before and after photos from RenuviaRX patients, shared with their permission.
BeforeAfterLost 33 lbs
“Tirzepatide changed my life for the better.”
Tamara M.
BeforeAfterLost 48 lbs
“I can finally play with my grandkids again.”
Michael S.
BeforeAfterLost 22 lbs
“I feel like in my 20s, more energy, lighter on my feet.”
Thomas J.
BeforeAfterLost 14 lbs
“Microdosing helped me to maintain my weight effortlessly.”
Sandra F.
Individual results vary and are not typical. Weight loss depends on medication, dose, diet, activity and following your plan.
How do they compare?
WHAT GLP-1 TREATMENT CAN DO
Stop fighting your appetite. Start losing weight.
- Quiet the constant "food noise" and between-meal cravings
- Feel full on smaller portions, without white-knuckling it
- Lose weight steadily, week after week, instead of yo-yo dieting
- A plan that adjusts with you: your physician tunes the dose as you progress
- Pharmacy-compounded in the US and delivered to your door
Your timeline to treatment
From personalized care to doorstep delivery, we make it simple.
Answer a few questions about your health and goals. It takes about 5 minutes and there's no consultation fee.
If treatment is right for you, your physician prescribes semaglutide or tirzepatide and sets a starting dose. Your card isn't charged until you're approved.
Ships free to your door with syringes, alcohol pads and clear instructions. You start on a low weekly dose to let your body adjust.
Many people notice smaller portions feel like enough and cravings get quieter. Your physician steps the dose up gradually as needed.
Your care team checks in regularly and adjusts your plan with you, so it keeps fitting your goals.
What's included in your RenuviaRX membership?
- Access to physician-supervised treatments
- Board-certified physician oversight
- Unlimited provider messaging
- Side effect management and protocol adjustments
- Progress tracking and check-ins
- Personalized dosing optimization
$79/first month
Applies to the semaglutide Microdose 3-month plan billed in full ($277): $99/mo for months 2-3, then $319 every 3 months. Not charged unless prescribed.
Questions we hear every day
Semaglutide Microdose starts at just $79 for your first month on the 3-month plan, billed in full at checkout: $277 for your first 3 months ($79, then $99/month), then $319 every 3 months. A month-to-month plan is also available at $99 for your first month, then $119/month. Semaglutide Personalized Dose is $109 for your first month, then $179/month, or $427 for 3 months. Tirzepatide Microdose is $149 for your first month, then $169/month, or $397 for 3 months. Tirzepatide Personalized Dose is $179 for your first month, then $249/month, or $497 for 3 months. Every plan includes your physician review, medication, injection supplies, free shipping and ongoing access to your care team. No insurance needed, and your card isn't charged unless a physician approves your prescription.
Semaglutide is a GLP-1 medication: it acts on one appetite hormone. Tirzepatide is a dual GLP-1 + GIP medication: it acts on two. Semaglutide costs less. Your physician helps you choose the one that fits your health history and goals.
Microdose keeps you on a low, steady weekly dose, for getting lean and staying lean; a lower dose usually means milder side effects. Personalized Dose starts low and steps up gradually as your physician directs, for people with more weight to lose. You choose at the end of your assessment, and your physician confirms the right plan before anything is prescribed.
No. Compounded medications are prepared by a licensed US pharmacy for an individual patient based on a prescription, and are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness or quality. Your vial contains semaglutide or tirzepatide with vitamin B6 (pyridoxine).
Treatment is for adults carrying extra weight, especially those with weight-related concerns such as high blood pressure or prediabetes. It isn't right for everyone: you shouldn't use it if you're pregnant or planning pregnancy, or have a personal or family history of medullary thyroid cancer or MEN 2. Complete the 5-minute assessment and a licensed physician reviews your full health history before prescribing.
Many people notice a quieter appetite within the first few weeks. Weight loss is gradual: you start on a low dose that your physician adjusts over time, and results depend on your dose, diet, activity and following your plan. Individual results vary.
The most common are nausea, diarrhea, vomiting, constipation, indigestion and reduced appetite. They're usually mild to moderate and most common right after a dose increase. Starting low and stepping up slowly helps, and your care team is available 24/7 if you have questions.
Once a week, a small subcutaneous injection in the stomach, thigh or upper arm with a fine insulin-style needle. Your kit includes step-by-step instructions, and most people are comfortable after their first dose.
Yes. There are no contracts: skip, pause or cancel anytime in your patient portal.
Read more about GLP-1 weight loss
From our medical team
Important safety information
What you should know before starting semaglutide or tirzepatide.
Do not use if you or a family member have had medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or if you are pregnant. Compounded medications are not FDA-approved.