A synthetic fragment of thymosin beta-4, a repair protein your own cells make, studied for how soft tissue recovers and how freely you move.
Subcutaneous injection
Price
$149 /month
Coming soon. Get notified and be first in line when it launches.
Chapter 01 · Recover
Bounce back faster
What it's studied for
TB-500 borrows the active region of thymosin beta-4, one of the most abundant repair proteins in the body. The research is early and mostly preclinical.
Thymosin beta-4 has been studied in animal models of muscle, skin and connective-tissue repair, where it appears to help repair cells reach damaged areas.
Because it's involved in how cells move and remodel tissue, TB-500 is often used in protocols aimed at mobility and stiffness after training.
Animal studies suggest thymosin beta-4 can help regulate inflammatory signaling after tissue stress.
TB-500 protocols commonly use fewer injections per week than many other peptides. Your physician sets the schedule.
The science
Thymosin beta-4 is present in nearly every cell. It manages actin, the protein scaffolding cells use to change shape and move.
TB-500 is a short synthetic copy of the region of thymosin beta-4 that binds actin, the part researchers believe drives much of its activity.
By managing the actin inside cells, thymosin beta-4 influences how repair cells migrate into damaged tissue and how new blood vessels form.
Unlike a local treatment, TB-500 is injected under the skin and circulates, which is why it's used for general recovery goals rather than one spot.
We summarize the published research as it stands, including what isn't known yet.
Evidence: Preclinical
What's been studied
What we don't know yet
Research summaries are for education, not a promise of results. TB-500 is a compounded medication and is not FDA-approved. Your physician will talk you through what to realistically expect.
How it's used
Your physician sets your dose, schedule and how long you take it. Here's what a typical protocol looks like.
Subcutaneous injection
A small subcutaneous injection under the skin of the belly or thigh, with a fine insulin needle.
Typical protocol
Protocols commonly start with one or two injections a week for several weeks, then taper. Your physician sets your dose and schedule.
In your package
Not a complete list. Your physician reviews your full health history.
Stack it with
Treatments people commonly add alongside TB-500. Your physician decides what fits your health and goals.
Your care
A physician in your corner, start to finish.
How it works
Tell us about your health, your goals and anything you've tried before. It takes a few minutes, on any device.
A physician reviews your history, medications and goals, checks for anything that would make a peptide a poor fit, and may message you with questions.
If peptide therapy is appropriate, your physician recommends a protocol (dose, schedule and length) and you see your price before you pay.
A licensed US pharmacy prepares your prescription and ships it free, with everything you need and clear instructions.
Message your care team anytime. Your physician can adjust, pause or stop your protocol based on how you're doing.
Questions
Straight answers about TB-500.
BPC-157 injections and TB-500 are $149 a month and MOTS-c is $199 a month; pricing for the other peptides will be announced at launch. Peptides aren't available to order yet: join the waitlist and we'll email you when your visit opens. Shipping is free and there's no insurance needed.
Thymosin beta-4 is a 43-amino-acid protein your cells make. TB-500 is a short synthetic peptide that copies the region of thymosin beta-4 thought to drive its repair activity. Much of the published research is on the full protein, not the fragment.
No. TB-500 is a compounded medication: it's prepared for you, from a prescription, by a licensed US pharmacy. Compounded medications are not FDA-approved, which means the FDA hasn't reviewed them for safety or effectiveness. That's why a licensed physician reviews your health history before anything is prescribed.
TB-500 protocols commonly use one or two subcutaneous injections a week, sometimes with a higher starting phase that tapers. Your physician sets your exact dose and schedule.
Reported side effects are usually mild: injection-site redness or irritation, temporary tiredness, headache or a flushed feeling. Human safety data are limited, so your physician will check in and adjust or stop your protocol if needed.
Yes, they're often prescribed together in recovery protocols. Your physician decides whether a combined protocol is appropriate for you.
TB-500 is prohibited under the World Anti-Doping Agency (WADA) code, in and out of competition. If you're subject to drug testing in your sport, don't use it, and tell your physician during your visit.
Websites selling peptides "for research use only" aren't pharmacies. There's no prescription, no physician and no assurance of what's actually in the vial. Your peptide is prescribed by a licensed physician after a medical review and prepared by a licensed US compounding pharmacy.
Important safety information
Not for use if you are pregnant or breastfeeding, have active cancer or a history of cancer, or are under 18. Prohibited in WADA-tested sport.
TB-500 is a synthetic peptide fragment of thymosin beta-4. Research on it is mostly preclinical, and long-term safety in people has not been established.
Possible side effects may include: injection-site redness, irritation or bruising, temporary fatigue, headache, and flushing.
Contraindications: TB-500 may not be appropriate if you are pregnant, planning a pregnancy or breastfeeding; have an active cancer or a history of cancer (because thymosin beta-4 influences cell migration and blood-vessel growth); are under 18; or have a known allergy to any component.
Athletes: TB-500 and other thymosin beta-4 derivatives are prohibited at all times under the World Anti-Doping Agency (WADA) code.
This therapy should only be used under the supervision of a licensed healthcare provider. Tell your physician about every medication and supplement you take.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Compounded medications are not FDA-approved.
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